The FAME group presented their work in the 13th European Nutrition Conference, Federation of European Nutrition Societies (FENS) on Oct 17th 2019 in Dublin, Ireland.

The presentation “The FAME Project - an overview“ was given by Prof. Matthias Schulze. He presented the partners, aims and the research that is currently taken part based on randomized trials on whole diets (PREDIMED, CORDIOPREV) and on specific fatty acid modulations (LIPGENE, RESET, DIVAS, SATgene) or polyphenol content (FLAVURS, CIRCLES) as well as the large-scale population-based cohort EPIC-Potsdam.

“Impact of dairy on human health: biomarkers of intake and cardiovascular risk” was presented by Prof. Julie Lovegrove, from the University of Reading. The emphasis was the discussion of associations between dairy intake and risk from CVD and cardiometabolic diseases, and the future potential for circulating fatty acids as valid novel biomarkers of dairy intake.

Prof. Anne Marie Minihane, from University of East Anglia (UEA), presented “The influence of genotype on fatty acid status and its impact on cardio-metabolic health”, where she discussed how circulating and tissue polyunsaturated fatty acid (PUFA) status is modulated by common variants in genes which influence PUFA synthesis, metabolism, transport, and cell uptake. There was a particular focus on the fatty acid desaturase (FADS) 1 and 2 and lipoxygenase (ALOX) genes. The presentation summarized available evidence and considered how it can be used to refine future dietary guidelines

The talk “Lipidomics and cardiometabolic risk in PREDIMED” was delivered by Dr. Miguel Ruiz Canela, where he showed lipidome patterns longitudinally associated with CVD and T2D, including analyses of their 1-year changes and the subsequent CVD/T2D risk in the context of a Mediterranean diet intervention trial.